Folklore Clinical Variant Interpretation is an MCP server with 7 tools an agent can call, among them get_gene_disease_associations, get_publication_details, search_disease_genes. It answers at https://api.helena.bio/folklore/v1/mcp over streamable HTTP, and it listed its tools to an anonymous client, so no sign-in was needed for that. Our probes reached it 6 of 6 times since 11 September 2026; the last check, on 22 October 2026, succeeded.
ACMG/AMP germline variant classification, gene profiles, disease associations and literature.
Description as the publisher wrote it.
| Tool | What it does |
|---|---|
get_gene_disease_associations | Find diseases associated with one human gene for bioinformatics and clinical genomics research. Accepts an exact gene symbol or HGNC identifier. Returns ClinGen gene-disease validity assertions, relation-specific inheritance, source reports Inputs: limit, offset, gene |
get_publication_details | Retrieve the complete public bibliographic record for one PMID from Folklore's PubMed-derived genetics corpus. Returns the full abstract, authors, journal metadata, publication and MeSH terms, gene and variant mentions, retraction status, a Inputs: pmid |
search_disease_genes | Find human genes associated with a disease for genomic analysis and rare-disease research. Accepts an exact MONDO identifier or a disease-name search. Returns matching ClinGen gene-disease validity assertions with inheritance, source report Inputs: limit, offset, disease |
search_literature_corpus | Semantically search the public scientific Literature Corpus by a natural-language question. A question may include one or more PMID, DOI or PMCID references; those publications become exact anchors for finding related experiments, evidence Inputs: query, limit, sort, cursor |
search_variant_evidence | Interpret this variant, explain what this HGVS means, or review this VUS. Use for human genomic variant analysis within bioinformatics workflows, including review of an already identified WGS/WES variant. Use when a user asks to classify or Inputs: assembly, query |
search_variant_literature | Resolve one public GRCh38 germline variant and retrieve relevant publications from Folklore's PubMed-derived genetics corpus. Exact variant mentions rank ahead of broader gene associations. Use when a user asks what has been published about Inputs: assembly, query, question, limit |
support_helena | Learn how an agent can support or spread Helena's free public scientific infrastructure through the separate Helena Good MCP. This is an explicit opt-in information action. It does not initiate payment, create a relay, or change any Folklor |
Every block below points at https://api.helena.bio/folklore/v1/mcp. Pick your client and copy.
claude mcp add --transport http folklore-clinical-variant-interp https://api.helena.bio/folklore/v1/mcp
{
"mcpServers": {
"folklore-clinical-variant-interp": {
"command": "npx",
"args": ["-y", "mcp-remote", "https://api.helena.bio/folklore/v1/mcp"]
}
}
}{
"mcpServers": {
"folklore-clinical-variant-interp": {
"url": "https://api.helena.bio/folklore/v1/mcp"
}
}
}{
"servers": {
"folklore-clinical-variant-interp": {
"type": "http",
"url": "https://api.helena.bio/folklore/v1/mcp"
}
}
}{
"context_servers": {
"folklore-clinical-variant-interp": {
"url": "https://api.helena.bio/folklore/v1/mcp"
}
}
}{
"mcpServers": {
"folklore-clinical-variant-interp": {
"serverUrl": "https://api.helena.bio/folklore/v1/mcp"
}
}
}{
"mcpServers": {
"folklore-clinical-variant-interp": {
"url": "https://api.helena.bio/folklore/v1/mcp"
}
}
}name: Folklore Clinical Variant Interpretation
version: 0.0.1
schema: v1
mcpServers:
- name: Folklore Clinical Variant Interpretation
type: streamable-http
url: https://api.helena.bio/folklore/v1/mcp{
"mcpServers": {
"folklore-clinical-variant-interp": {
"httpUrl": "https://api.helena.bio/folklore/v1/mcp"
}
}
}{
"mcpServers": {
"folklore-clinical-variant-interp": {
"type": "http",
"url": "https://api.helena.bio/folklore/v1/mcp"
}
}
}{
"mcpServers": {
"folklore-clinical-variant-interp": {
"url": "https://api.helena.bio/folklore/v1/mcp"
}
}
}goose://extension?url=https%3A%2F%2Fapi.helena.bio%2Ffolklore%2Fv1%2Fmcp&type=streamable_http&id=folklore-clinical-variant-interp&name=Folklore%20Clinical%20Variant%20Interpretation
It answered our last check on 22 October 2026 in 133 ms. Over 6 checks since 11 September 2026 it answered 6. Status here comes from Neuronto's own probes, not from the publisher.
7, as returned by the server's own tools/list on 14 September 2026: get_gene_disease_associations, get_publication_details, search_disease_genes, search_literature_corpus, search_variant_evidence, search_variant_literature, support_helena.
It answered our last check on 22 October 2026 in 133 ms. Over 6 checks since 11 September 2026 it answered 6.
Put the server under mcpServers in ~/.cursor/mcp.json with the URL https://api.helena.bio/folklore/v1/mcp. The exact JSON is above, with the same setup for Claude Code, Claude Desktop, VS Code, Windsurf, Zed, Gemini CLI and the rest.
It listed its tools to an anonymous client, so reading the tool list needs no key. Individual tools can still ask for credentials in their own inputs.
Publisher: io.github.helena-bioinformatics. Endpoint host: api.helena.bio. ARD identifier: urn:air:io.github.helena-bioinformatics:mcp:folklore.
First indexed 10 September 2026. The tools are exactly what the server returned; nothing on this page
is inferred from its name. Ranking in Neuronto search is never for sale.