Chembl is an MCP server with 7 tools an agent can call, among them chembl_dataframe_describe, chembl_dataframe_query, chembl_get_assay. It answers at https://chembl.caseyjhand.com/mcp over streamable HTTP, and it listed its tools to an anonymous client, so no sign-in was needed for that. Our probes reached it 6 of 6 times since 11 September 2026; the last check, on 21 October 2026, succeeded.
Link compounds to protein targets, rank bioactivity, and look up drug mechanisms and indications.
Description as the publisher wrote it.
| Tool | What it does |
|---|---|
chembl_dataframe_describe | List the tables and columns staged on a canvas by chembl_get_bioactivities — inspect before calling chembl_dataframe_query to write correct SQL. Returns each table with its row count, kind (table | view), and column names + types. Requires Inputs: canvas_id |
chembl_dataframe_query | Run a read-only SQL SELECT over the bioactivity rows chembl_get_bioactivities spilled to a canvas — rank, group, dedupe, and aggregate across the FULL set, not the inline preview. Reference each staged table by the name chembl_get_bioactivi Inputs: canvas_id, sql |
chembl_get_assay | Assay provenance behind a bioactivity row: description, type (binding / functional / ADMET / toxicity), the target it measures, organism, and ChEMBL's 1–9 confidence score (9 = direct assay on the protein target, lower = homologous or indir Inputs: assay_chembl_id |
chembl_get_bioactivities | The flagship compound↔target bioactivity bridge: measurements for a molecule (target deconvolution / selectivity), a target (lead finding), or both together (how potently one compound hits one target). Supply at least one of molecule_chembl Inputs: molecule_chembl_id, target_chembl_id, standard_type, pchembl_value_min, potency_view, assay_type |
chembl_get_drug_info | Pharmacology for a drug (molecule): mechanism(s) of action, the molecular target(s) it acts on, action type (inhibitor / agonist / …), first-approval year, and clinical indications with the max phase reached for each. Supply molecule_chembl Inputs: molecule_chembl_id |
chembl_search_molecules | Discovery entry point for compounds. Find by name / ChEMBL ID / InChIKey with the default search_type=name (supply query), or run a structure search with search_type exact | similarity | substructure (supply structure as a SMILES). At least Inputs: query, structure, search_type, similarity_threshold, max_phase_min, limit |
chembl_search_targets | Resolve a protein/gene/UniProt accession to the ChEMBL target ID that chembl_get_bioactivities needs for the target→leads workflow. Supply at least one of accession (UniProt, e.g. P00533), gene_symbol (e.g. EGFR), or query (free-text name); Inputs: query, accession, gene_symbol, organism, target_type, limit |
Every block below points at https://chembl.caseyjhand.com/mcp. Pick your client and copy.
claude mcp add --transport http chembl https://chembl.caseyjhand.com/mcp
{
"mcpServers": {
"chembl": {
"command": "npx",
"args": ["-y", "mcp-remote", "https://chembl.caseyjhand.com/mcp"]
}
}
}{
"mcpServers": {
"chembl": {
"url": "https://chembl.caseyjhand.com/mcp"
}
}
}{
"servers": {
"chembl": {
"type": "http",
"url": "https://chembl.caseyjhand.com/mcp"
}
}
}{
"context_servers": {
"chembl": {
"url": "https://chembl.caseyjhand.com/mcp"
}
}
}{
"mcpServers": {
"chembl": {
"serverUrl": "https://chembl.caseyjhand.com/mcp"
}
}
}{
"mcpServers": {
"chembl": {
"url": "https://chembl.caseyjhand.com/mcp"
}
}
}name: Chembl
version: 0.0.1
schema: v1
mcpServers:
- name: Chembl
type: streamable-http
url: https://chembl.caseyjhand.com/mcp{
"mcpServers": {
"chembl": {
"httpUrl": "https://chembl.caseyjhand.com/mcp"
}
}
}{
"mcpServers": {
"chembl": {
"type": "http",
"url": "https://chembl.caseyjhand.com/mcp"
}
}
}{
"mcpServers": {
"chembl": {
"url": "https://chembl.caseyjhand.com/mcp"
}
}
}goose://extension?url=https%3A%2F%2Fchembl.caseyjhand.com%2Fmcp&type=streamable_http&id=chembl&name=Chembl
It answered our last check on 21 October 2026 in 548 ms. Over 6 checks since 11 September 2026 it answered 6. Status here comes from Neuronto's own probes, not from the publisher.
7, as returned by the server's own tools/list on 13 September 2026: chembl_dataframe_describe, chembl_dataframe_query, chembl_get_assay, chembl_get_bioactivities, chembl_get_drug_info, chembl_search_molecules, chembl_search_targets.
It answered our last check on 21 October 2026 in 548 ms. Over 6 checks since 11 September 2026 it answered 6.
Put the server under mcpServers in ~/.cursor/mcp.json with the URL https://chembl.caseyjhand.com/mcp. The exact JSON is above, with the same setup for Claude Code, Claude Desktop, VS Code, Windsurf, Zed, Gemini CLI and the rest.
It listed its tools to an anonymous client, so reading the tool list needs no key. Individual tools can still ask for credentials in their own inputs.
Publisher: io.github.cyanheads. Endpoint host: chembl.caseyjhand.com. ARD identifier: urn:air:io.github.cyanheads:mcp:chembl-mcp-server.
First indexed 10 September 2026. The tools are exactly what the server returned; nothing on this page
is inferred from its name. Ranking in Neuronto search is never for sale.